Then the Lord will make thy plagues wonderful,.... Visible, remarkable, distinguishable, and astonishing to all that see them:
and the plagues of thy seed; for they were to continue, as they have done, With their posterity, age after age:
[even] great plagues, and of long continuance; great as to quality and quantity, and firm, sure, lasting, and durable; the word used is rendered "sure" in Isaiah 55:3; sure by prophecy and in the event; and which when inflicted remained, as they have 1700 years; all which might be believed as certain, or what would certainly come to pass, and be depended on:
and sore sicknesses, and of long continuance; besides those diseases mentioned Deuteronomy 28:27; or however others including them.