Persecute and destroy them in anger,.... As they have persecuted the people of God, do thou persecute them; and never leave pursuing them untie thou hast made a full end of them, as the effect of vindictive wrath and vengeance:
from under the heavens of the Lord; which are made by him, and in which he dwells; let them not have the benefit of them, nor so much as the sight of them; but let them perish from under them, Jeremiah 10:11.