And if a man shall lie with his uncle's wife,.... His uncle being dead, and he marry her, which is forbidden, Leviticus 18:14;
he hath uncovered his uncle's nakedness: his wife's, which was his, and therefore the kindred too near for a man to marry in, and such a copulation must be incestuous:
they shall bear their sin; "both" of them, as the Vulgate Latin, as before, Leviticus 20:19; the punishment of it, as follows:
they shall be childless; which Jarchi and other Jewish writers interpret, if they had any children at this time, that is, by a former marriage, they should die and be buried before them, which was reckoned a great punishment, see Jeremiah 22:30.