11. Depart from the way. The amount of what is stated is, that when the prophets are set aside, the Lord is also rejected and set aside, and no regard is paid to him. Wicked men pretend the contrary, for they are ashamed to acknowledge so great wickedness. But they gain nothing by it; for God wishes that we should listen to him by means of those to whom he gave injunctions to declare his will to us, and to administer the doctrine of the word. If therefore it is our duty to listen to God, if we are bound to pay him any homage, we ought to shew it by embracing his word, as it is contained in the writings of the prophets and evangelists. This ought to be carefully observed in commendation of the word; for they who set it aside act as if they denied that he is God.
Cause the Holy One of Israel to depart. Here he again points out the cause of so great wickedness, which doubles their guilt; namely, that God does not spare or flatter their vices, but acts the part of a good and skillful physician. Men desire to be flattered, and cannot patiently endure that God should threaten them. Hence it comes that men hate and reject the word. Hence proceeds the furious attack on the prophets, whose reproofs and threatenings they cannot endure; for there is no reason why men should revolt from the government of God, but because they take delight in what is wrong and crooked, and abhor the right way. Appropriately, therefore, does the Prophet join these two things, dislike of heavenly doctrine and hatred of uprightness.