1 Peter 2:22 - Clarke's commentary and critical notes on the Bible

Who did no sin, neither was guile found in his mouth: Who did no sin - He suffered, but not on account of any evil he had either done or said. In deed and word he was immaculate, and yet he was exposed to suffering; expect the same, and when it comes bear it in the same spirit. It is very likely that the apostle mentions guile, because those who do wrong generally strive to screen themselves by prevarication and lies. These words appear to be a quotation from Isaiah 53:9.