Preach the word; be instant in season, out of season; reprove, rebuke, exhort with all longsuffering and doctrine. Preach the word - Κηρυξον τον λογον· Proclaim the doctrine, the doctrine of Christ crucified, for the sins of the whole world; the doctrine, that the Gentiles are invited to be fellow heirs with the Jews, and that for Jews and Gentiles there is no salvation but by faith in Christ.
Be instant in season, out of season - Επιστηθι ευκαιρως, ακαιρως. Be urgent whether the times be prosperous or adverse, whenever there is an opportunity; and when there is none, strive to make one. The Judge is at the door, and to every man eternity is at hand! Wherever thou meetest a sinner, speak to him the word of reconciliation. Do not be contented with stated times and accustomed places merely; all time and place belong to God, and are proper for his work. Wherever it can be done, there it should be done. Satan will omit neither time nor place where he can destroy. Omit thou none where thou mayest be the instrument of salvation to any.
Reprove - Ελεγξον· Confute, the false teacher.
Rebuke - Επιτιμησον· Reprove cuttingly and severely those who will not abandon their sins.
Exhort - Παρακαλεσον· Comfort the feeble-minded, the diffident and the tempted.
With all long-suffering - In reference to each and all of these cases.
And doctrine - The different modes of teaching suited to each.