And these things will they do unto you, because they have not known the Father, nor me. Because they have not known the Father - See on John 15:25 (note). Ignorance of the benevolence of God, and of the philanthropy of Christ, is the grand fountain whence all religious persecution and intolerance proceed.
Related Commentaries of John 16:3
John 16:3
3 And these things will they do unto you, because they have not known the Father, nor me.