Not giving heed to Jewish fables, and commandments of men, that turn from the truth. Not giving heed to Jewish fables - See on 1 Timothy 1:4 (note); 1 Timothy 4:7 (note).
Commandments of men - The injunctions of the scribes and Pharisees, which they added to the law of God.
That turn from the truth - For such persons made the word of God of none effect by their traditions. Sometimes the verb αποστρεφομαι signifies to be averse from, slight, or despise. So, here, the persons in question despised the truth, and taught others to do the same.