And the king of the south shall be strong, and one of his princes; and he shall be strong above him, and have dominion; his dominion shall be a great dominion.
And the king of the south shall be strong. Here the prophet leaves Asia and Greece, and takes up Egypt and Syria, these being in continual conflict under Alexander's successors, entailing misery on Judea, which lay between the two. Holy Scripture handles external history only so far as it is connected with God's people Israel (Jerome). Tregelles puts a chasm between Daniel 11:4-5, making the transition to the final Antichrist here, answering to the chasm (in his view) at Daniel 8:22-23.
King of the south - literally, the king of mid-day: "Egypt" (Daniel 11:8; Daniel 11:42): Ptolemy Soter, son of Lagus. He took the title "king," whereas Lagus was but 'governor.'
And one of his princes; and he shall be strong above him - Seleucus, at first a satrap of Ptolemy Lagus, but from312 BC king of the largest empire after that of Alexander (Syria, Babylon, Media, etc.), and called therefore Nicator - i:e., Conqueror. Connect the words thus: 'And one of his (Ptolemy's) princes, even he (Seleucus) shall be strong above him' (above Ptolemy, his former master).