And his power shall be mighty, but not by his own power: and he shall destroy wonderfully, and shall prosper, and practise, and shall destroy the mighty and the holy people.
His power shall be mighty, but not by his own power - which in the beginning was "little" (Daniel 8:9; Daniel 7:8); but by gaining over others through "craft," the once little horn became "mighty" (cf. Daniel 8:25; Daniel 11:23, "After the league made with him he shall work deceitfully: for he shall come up, and shall become strong with a small people"). To be fully realized by Antichrist, He shall act by the power of Satan, who shall then be permitted to work through him in unrestricted license, such as he has not now (Revelation 13:2, "The dragon gave him (the beast) his power, and his seat, and great authority"); hence, the ten kingdoms shall give the beast their power (2 Thessalonians 2:9-12; Revelation 17:13, "These (ten kings) have one mind, and shall give their power and strength unto the beast").
And shall prosper, and practice - prosper in all that he attempts (Daniel 8:12).
And shall destroy the mighty and the holy people - his persecutions are especially directed against the Jews.