Therefore, O thou son of man, speak unto the house of Israel; Thus ye speak, saying, If our transgressions and our sins be upon us, and we pine away in them, how should we then live?
Thus ye speak, saying, If our transgressions and our sins be upon us - i:e., If their guilt remain on us.
And we pine away in them - if we suffer the penalty threatened for them in Ezekiel 24:23 ("Ye shall pine away for your iniquities"), according to the law (Leviticus 26:39).
How should we then live? - as thou dost promise in Ezekiel 33:5 (cf. Ezekiel 37:11; Isaiah 49:14).