O Israel, thou hast destroyed thyself; but in me is thine help.
O Israel, thou hast destroyed thyself; but in me. Thou and ME stand in contrast.
Hast destroyed thyself - Literally, thy destruction is of thyself (Proverbs 6:32, "He that doeth it (adultery) destroyeth his own soul;" Proverbs 8:36).
In me is Thine help - literally, in thine help - (cf. Deuteronomy 33:26). Hadst thou rested thy hope in me, I would have been always ready at hand for thy help (Grotius).