Sing unto the LORD a new song, and his praise from the end of the earth, ye that go down to the sea, and all that is therein; the isles, and the inhabitants thereof.
Sing unto the Lord a new song - such as has never before been sung, called for by a new manifestation of God's grace, to express which no hymn for former mercies would be appropriate. The new song shall be sung when the Lord shall reign in Jerusalem, and all "nations shall flow unto it" (Isaiah 2:2; Isaiah 26:1; Revelation 5:9; Revelation 14:3).
Ye that go down to the sea - whose conversion will be the means of diffusing the Gospel to distant lands.
All that is therein - all the living creatures that fill the sea (Psalms 96:11) (Maurer). Or, all sailors and voyagers (Gesenius). But these were already mentioned in the previous clause: there he called on all who go upon the sea; in this clause all animals in the sea; so in Isaiah 42:11 he calls on the inanimate wilderness to lift up its voice. External nature shall be so renovated as to be in unison with the moral renovation.