Thus saith the LORD that made thee, and formed thee from the womb, which will help thee; Fear not, O Jacob, my servant; and thou, Jesurun, whom I have chosen.
Thus saith the Lord that ... formed thee from the womb - (so Isaiah 44:24; Isaiah 49:1; Isaiah 49:5.) The sense is similar to that in Isaiah 1:2, "I have nourished and brought up children." (See Isaiah 43:1; Isaiah 43:7.)
Fear not ... thou, Jesurun - a diminutive term of endearment applied to Israel. The full title of affection was Israelun: contracted, it became Jeshurun, with an allusion to the Hebrew root, jashar, 'upright,' 'perfect' (see note on "he that is perfect," Isaiah 42:19) (Gesenius). Or rather, it is a diminutive of jashur, or jashar, the upright dear people of God (Deuteronomy 32:15).