Then I said, I have laboured in vain, I have spent my strength for nought, and in vain: yet surely my judgment is with the LORD, and my work with my God.
Then I said. "I" - Messiah.
Laboured in vain - comparatively, in the case of the greater number of His own countrymen, and of His own 'relatives.' "He came unto His own, and His own received Him not" (Isaiah 53:1-3; Luke 19:14; John 1:11; John 7:5). Only one hundred and twenty disciples met in the upper room after His personal ministry was ended (Acts 1:15). Five hundred are mentioned as having at one time seen Him after His resurrection (1 Corinthians 15:6).
(Yet) surely my judgment (is) with the Lord, and my work with my God - ultimately God will do justice to my cause, and reward (margin for work, cf. Isaiah 40:10; Isaiah 62:11) my labours and sufferings. He was never 'discouraged' (Isaiah 42:4; Isaiah 50:7; Isaiah 50:10). He calmly, in spite of seeming ill success for the time, left the result with God, confident of final triumph (Isaiah 53:10-12; 1 Peter 2:23). So the ministers of Christ (1 Corinthians 4:1-5; 1 Peter 4:19).