Therefore my people are gone into captivity, because they have no knowledge: and their honourable men are famished, and their multitude dried up with thirst.
Therefore my people are gone into captivity - the prophet sees the future as if it were before his eyes.
Because (they have) no knowledge - because of their foolish recklessness and willful ignorance as to God, His law, and His visitations of Providence, chastisement, and grace (Isaiah 5:12; Isaiah 1:3; Hosea 4:6, "My people are destroyed for lack of knowledge; because thou hast rejected knowledge ... thou hast forgotten the law of thy God;" Luke 19:44).
Their honourourable men (are) famished - awful contrast to their luxurious feasts (Isaiah 5:11-12); Hebrew, 'their glory (are) men (literally, mortals) of famine.'
And their multitude - plebeians, in contradistinction to the "honourable men" or nobles.
Dried up with thirst - (Psalms 107:4-5.) Contrast to their drinking (Isaiah 5:11). In their deportation and exile they shall hunger and thirst.