I beseech Euodias, and beseech Syntyche, that they be of the same mind in the Lord.
Euodias and Syntyche were two women at variance; probably deaconesses or persons of influence (Acts 17:12). He repeats "I beseech," as if he would admonish each separately with impartiality, both being equally to blame.
In the Lord - the element of Christian union: for those "in the Lord" to be at variance is an utter inconsistency.