Open thy mouth for the dumb in the cause of all such as are appointed to destruction.
Open thy mouth for the dumb - i:e., for those who cannot defend themselves in the courts of justice.
In the cause of all such as are appointed to destruction - literally, 'the sons of passing away.' Maurer, 'the sons of abandonment,' or orphanage - i:e., sons left orphans by their deceased parents; Hebrew, benee chaloph. Imitate God who is peculiarly the Patron of the widow and the orphan.