Uphold me according unto thy word, that I may live: and let me not be ashamed of my hope.
Uphold me according unto thy word, that I may live - Do not let me either be destroyed or seduced by the "evil-doers" (Psalms 119:115).
And let me not be ashamed (i:e., disappointed) of my hope - of salvation (Psalms 25:2-3; Romans 5:5; Romans 9:33).