Psalms 69:21 - Joseph Benson’s Commentary on the Old and New Testaments

They gave me gall for my meat Instead of affording me that pity and comfort which my condition required, they barbarously added to my affliction. These words were only metaphorically fulfilled in David, but were properly and literally accomplished in Christ; the description of whose sufferings, it seems, was principally intended here by the Holy Ghost, who therefore directed David's pen to these words. And hence what follows may as truly, and perhaps more properly, be considered as predictions of the punishment which should be inflicted on the persecutors of our Lord, than as imprecations of David against his enemies.