For it is sanctified by the word of God - By the authority or permission of God. It would be profane or unholy if he had forbidden it; it is made holy or proper for our use by his permission, and no command of “man” can make it unholy or improper; compare Genesis 1:29; Genesis 9:3.
And prayer - If it is partaken of with prayer. By prayer we are enabled to receive it with gratitude, and everything that we eat or drink may thus be made a means of grace.