For it is sanctified: sanctified in this place signifies made pure, or lawful to be used. By the word of God; by the gospel, which declares it so, Acts 10:15; or by God's ordination, which hath so determined it. And prayer; and prayer to God for a blessing upon it.
Related Commentaries of 1 Timothy 4:5
1 Timothy 4:5
5 For it is sanctified by the word of God and prayer.