Ye prophets and ministers of God, comfort and encourage God's people, who are now ready to faint, with hopes and assurance of that salvation which, in due time, I will work for them. He mentions hands and knees, because the strength and weakness of any man eminently appears in those parts.
Related Commentaries of Isaiah 35:3
Isaiah 35:3
3 Strengthen ye the weak hands, and confirm the feeble knees.