From thy spirit; either,
1. From the Holy Ghost, the third person in the Trinity: or,
2. From thee, who art a Spirit, and therefore canst penetrate into the most secret parts: or,
3. From thy mind or understanding, of which he is here speaking, as this word seems to be taken, Isaiah 40:13, compared with Romans 11:34; for what there is called the spirit of the Lord, is here called the mind of the Lord. And as the Spirit of God is oft used in Scripture for its gifts and graces, so the spirit of God in this place may be put for that knowledge which is an attribute or action of God. From thy presence; a man can go to no place which is out of thy sight.