Who can have compassion— The word Μετριοπαθειν signifies "to treat with moderation and gentleness." See the margin. "Who is able to proportion his compassion to those that are ignorant, and wandering from the exact paths of God's commandments, because he himself also is incident to infirmity." The ignorant and erroneous are here put, by a usual figure, for those who wander, or sin, through ignorance; the case, in which priests, appointed by men, were to offer sacrifices for them.
Related Commentaries of Hebrews 5:2
Hebrews 5:2
2 Who cana have compassion on the ignorant, and on them that are out of the way; for that he himself also is compassed with infirmity.