Isaiah 51:18 [There is] none to guide her among all the sons [whom] she hath brought forth; neither [is there any] that taketh her by the hand of all the sons [that] she hath brought up.
Ver. 18. There is none to guide her.] This was a point next the worst, as we say. She was without prudent and pious magistrates and ministers, or other friends to advise her; and so she was δισκακοδαιμων - twice miserable. Christ hath promised all his, "I will not leave you destitute," or orphans.
Among all her sons.] Who should see to their aged parents and sublevate them, as pious Aeneas did, and as Scipio, who therehence had his name; but Zion's sons were themselves in a dreadful plight, Isa 51:20 and in an ill case to relieve their mother.