There is none to guide her among all the sons whom she hath brought forth; neither is there any that taketh her by the hand of all the sons that she hath brought up.
(There is) none to guide her among all the sons (whom) she hath brought forth. Following up the image in Isaiah 51:17, intoxicated and confused by the cup of God's anger, she has none to guide her in her helpless state: she has not yet awakened out of the sleep caused by that draught. This cannot apply to the Babylonian captivity; because in it they, had Ezekiel and Daniel, Ezra and Nehemiah, as 'guides,' and soon awoke out of that sleep; but it applies to the Jews now, and will be still more applicable in their coming oppression by Antichrist.