Moab — Tho' they are a most vile nation. Zoar — Zoar was a town bordering upon Moab. Of destruction — Such a cry as men send forth when they are just falling into the pit of destruction.
Related Commentaries of Isaiah 15:5
Isaiah 15:5
5 My heart shall cry out for Moab; his fugitives shall flee unto Zoar, an heifer of three years old: for by the mounting up of Luhith with weeping shall they go it up; for in the way of Horonaim they shall raise up a cry of destruction.