The wolf, &c. — God here promises to take off the fierceness of the spirits of his peoples enemies, so that they shall live quietly and peaceably together. And dust — God promises a time of tranquility to his church under the metaphor of serpents eating the dust, their proper meat, Genesis 3:14, instead of flying upon men: it signifies such a time, when wicked men shall no more eat up the people of God.
Related Commentaries of Isaiah 65:25
Isaiah 65:25
25 The wolf and the lamb shall feed together, and the lion shall eat straw like the bullock: and dust shall be the serpent's meat. They shall not hurt nor destroy in all my holy mountain, saith the LORD.