Giving thanks always for all things unto God and the Father in the name of our Lord Jesus Christ; Giving thanks always - God is continually loading you with his benefits; you deserve nothing of his kindness; therefore give him thanks for his unmerited bounties.
God and the Father - That is: God, who is your Father, and the Father of mercies. See the observations on the Greek article at the end of this epistle.
In the name of our Lord Jesus - He is the only mediator; and through him alone can ye approach to God; and it is for his sake only that God will hear your prayers or receive your praises.