And the beginning of his kingdom was Babel, and Erech, and Accad, and Calneh, in the land of Shinar. The beginning of his kingdom was Babel - בבל babel signifies confusion; and it seems to have been a very proper name for the commencement of a kingdom that appears to have been founded in apostasy from God, and to have been supported by tyranny, rapine, and oppression.
In the land of Shinar - The same as mentioned Genesis 11:2. It appears that, as Babylon was built on the river Euphrates, and the tower of Babel was in the land of Shinar, consequently Shinar itself must have been in the southern part of Mesopotamia.