Behold, ye are of nothing, and your work of nought: an abomination is he that chooseth you. Your work of naught "Your operation is less than naught" - For מאפע meepha, read מאפס meephes; so the Chaldee and Vulgate. A manifest error of the text; compare Isaiah 40:17. The rabbins acknowledge no such error, but say that the former word signifies the same with the latter, by a change of the two letters ס samech and ע ain. - Sal ben Melec in loc.
Related Commentaries of Isaiah 41:24
Isaiah 41:24
24 Behold, ye are of nothing,i and your work of nought: an abomination is he that chooseth you.