Behold, ye are of nothing, and your work of nought: an abomination is he that chooseth you.
Ye are of nothing - (note, Isaiah 40:17.)
And your work of nought. The Hebrew text х mee'aapa` (H659), of the work of a viper] is here corrupt. So the English version treats it [it ought to be mee'aapec: cf. Isaiah 40:17].
Abomination - abstract for concrete; not merely abominable but the essence of whatever is so (Deuteronomy 18:12).
(Is he that) chooseth you - as an object of worship.