And be not drunk with wine, wherein is excess; but be filled with the Spirit;
Wherein - not in the wine (1 Timothy 5:23), but in 'becoming drunk' with it.
Excess, х asootia (G810)] - 'dissoluteness;' literally, unsavingness; unrestrained recklessness.
But be filled with (literally, IN) the Spirit. In inspiration the person was "filled" with ecstatic exhilaration, like that caused by wine; hence, the two are connected (cf. Acts 2:13-18). Many prophets-e.g., John Baptist-abstained from wine, an order that the world might distinguish the ecstasy caused by the Spirit from that caused by wine. So in ordinary Christians, the Spirit dwells not in the mind that seeks excitement, but in the well-balanced prayerful mind. Such express their joy, not in drunken or worldly songs, but in Christian hymns of thankfulness.