But your iniquities have separated between you and your God, and your sins have hid his face from you, that he will not hear. Your sins have hid (his) face from you - Hebrew, have caused Him to hide His face from you (Lamentations 3:44). The awful picture here given of their iniquities, which separated between them and God, is peculiarly applicable to the period which immediately preceded the destruction of their state by Rome.
Related Commentaries of Isaiah 59:2
Isaiah 59:2
2 But your iniquities have separated between you and your God, and your sins have hida his face from you, that he will not hear.