Lift up your hands in the sanctuary, and bless the LORD.
Lift up your hands. The gesture signified elevation of the heart in prayer (Psalms 28:2).
In the sanctuary. The Chaldaic Targum has 'with holiness;' the Syriac, 'to holiness;' the Septuagint, Vulgate, Ethiopic, and Arabic, 'toward the sanctuary.' Psalms 27:2 favours the last.