Deliver me from all my transgressions: make me not the reproach of the foolish.
Deliver me from all my transgressions - alike from their guilt, power, and penalty; especially from being delivered up to mine enemies (cf. next clause).
Make me not the reproach of the foolish. This is the "stroke" of God which he dreads (Psalms 39:10). He hath 'the wicked still before him' (Psalms 39:1, note), but his language shows that he now feels his "transgressions" to be the true cause of his sufferings not any harshness or unrighteousness in God, such as he had heretofore complained of.