Revelation 16:3 - Joseph Benson’s Commentary on the Old and New Testaments

And the second angel poured out his vial upon the sea, &c. This, says the same pious author, must begin where the other ended, as to the period of time. Now I find that in the year 1566 the wars between the king of Spain and the states of the Netherlands began. The Spaniards, indeed, were often victorious at first, yet they were at length compelled to declare them free states. It was then that the sea became blood to the Romanists, their votaries being miserably defeated in their expectations. For after their cruelties under the duke of Alva, in the Low Countries, and their massacre of the Protestants, in France and other places, the scene was changed very quickly; so that, in the year 1588, the Spaniards lost their vast armada, and ever after declined in their power. And the duke of Guise, the inveterate enemy of the Protestants, was killed the same year; and A.D. 1598 Philip II. of Spain died, being eaten of vermin: the edict of Nantz was also issued the same year in France in favour of the Protestants. So that, as the Reformed interest was in peace everywhere, and conquered in Holland and England, the Popish party, on the other hand, saw Spain, the late terror of the Protestants, brought to a languishing condition, and all their allies weary of wars and persecutions. And as in the year 1609 the truce was made between the Spaniards and the Dutch, so the war, though renewed and carried on afterward, became languid and faint, so as hardly to be regarded by either party, especially the Dutch, who were generally victorious and successful. Hence, as the period of this vial began in 1566, so we may reckon it continued about fifty years, namely, till the year 1617, when the third vial began.