Innocent blood; the blood of those prophets and righteous men who either reproved his sinful practices, or refused to comply with his wicked commands and worship. Beside his sin, i.e. his idolatry, which is elsewhere called evil, and corruption, and here sin, by way of eminency; which is the more considerable, because it is here compared with horrid cruelty, and implied to be worse than that, and more abominable in God's sight, because it doth more directly and immediately strike at the glory and purity of the Divine Majesty, by respect unto which all sins are to be measured. And this expression God here useth in opposition to the gross error of most men, who look upon idolatry as a small sin, as a mere mistake of the mind, as the fruit of a good intention, and as an excess proceeding from zeal in religion.
Related Commentaries of 2 Kings 21:16
2 Kings 21:16
16 Moreover Manasseh shed innocent blood very much, till he had filled Jerusalem from one end to another; beside his sin wherewith he made Judah to sin, in doing that which was evil in the sight of the LORD.