The lion is come up from his thicket, i.e. Nebuchadnezzar, called here a lion from his fierceness and strength, Proverbs 30:30; a metaphor; especially in this expedition; see Isaiah 5:27-29 shall come up from Babylon, where his chief seat is, Daniel 4:30; as lions are principally among the thickets of the forest, in coverts; this place being so remote and hid from them, that they least expected trouble to arise from thence. The destroyer of the Gentiles; another description of the same person, of whose destroying armies the nations have had woeful experience, Isaiah 14:16,17, called the hammer of the whole earth, Jeremiah 50:23: q.d. And how shall you think to escape him? Is on his way, i.e. as it is expressed in the next clause, he is gone forth from his place, he is already upon his march. To make thy land desolate, i.e. with a resolution so to do. Shall be laid waste, without an inhabitant, i.e. as places uninhabited soon lie waste, and are overgrown with grass, as the notation of the word seems to import.
Related Commentaries of Jeremiah 4:7
Jeremiah 4:7
7 The lion is come up from his thicket, and the destroyer of the Gentiles is on his way; he is gone forth from his place to make thy land desolate; and thy cities shall be laid waste, without an inhabitant.