The lion is come up from his thicket, and the destroyer of the Gentiles is on his way; he is gone forth from his place to make thy land desolate; and thy cities shall be laid waste, without an inhabitant.
Lion - Nebuchadnezzar, and the Chaldeans (Jeremiah 2:15; Jeremiah 5:6; Daniel 7:4, "The first (of the four beasts, namely, the Babylonian king) was like a lion").
His thicket - lair: Babylon.
Destroyer of the Gentiles - rather, 'the nations' (Jeremiah 25:9).